Illegal — No Active Legislation
Updated 2026-04-20
Psilocybin Laws in Oklahoma
Psilocybin is illegal in Oklahoma with no active legislation. Oklahoma has conservative drug policies, though it has a significant medical cannabis industry.
Current Legal Status
Illegal — No Active Legislation
Psilocybin is a Schedule I controlled substance under Oklahoma law. Possession is a felony; distribution carries serious felony charges.



Key Legislation
No psilocybin legislation has been introduced in the Oklahoma Legislature.
Clinical Trials
University of Oklahoma Health Sciences Center has broad research programs. Check ClinicalTrials.gov for Oklahoma City and Tulsa area enrolling studies.
Advocacy Organizations
No Oklahoma-specific psychedelic advocacy organizations are currently active.
Related Resources
See how Oklahoma compares to neighboring states and find therapy options for residents: