Illegal — No Active Legislation
Updated 2026-04-20
Psilocybin Laws in Iowa
Psilocybin is illegal in Iowa with no active legislation. Iowa has conservative drug policies and has not moved to legalize cannabis for recreational use.
Current Legal Status
Illegal — No Active Legislation
Psilocybin is a Schedule I controlled substance under Iowa law. Possession is a serious misdemeanor for small amounts; larger amounts and distribution carry felony charges.



Key Legislation
No psilocybin legislation has been introduced in the Iowa General Assembly.
Clinical Trials
University of Iowa has broad research programs. Check ClinicalTrials.gov for Iowa City-area enrolling psilocybin studies.
Advocacy Organizations
No Iowa-specific psychedelic advocacy organizations are currently active.
Related Resources
See how Iowa compares to neighboring states and find therapy options for residents: