Psilocybin Laws in Illinois
Illinois has introduced psilocybin reform legislation and Chicago has seen growing advocacy for decriminalization. Illinois legalized recreational cannabis in 2020 with an equity focus, and advocates are using that framework as a model for psilocybin reform.
Current Legal Status
Active Legislation
Psilocybin remains Schedule I under Illinois law. Bills to establish a therapeutic psilocybin program have been introduced and are under active debate. Chicago advocacy groups have pushed for a city-level decriminalization resolution.
Key Legislation
SB 3074 (2024) proposed a psilocybin therapeutic services act modeled on Oregon's framework. HB 4873 (2025) introduced a broader natural medicine decriminalization bill. Both are in committee as of 2026.
Clinical Trials
Northwestern University, University of Chicago, and Rush University Medical Center have participated in psilocybin research. Multiple trials enrolling in the Chicago area.
Advocacy Organizations
Illinois Psilocybin Society, Chicago Psychedelic Society, Decriminalize Nature Chicago, Healing Advocacy Fund.
Related Resources
People in Illinois
- Harriet de Wit, Ph.D. — Professor of Psychiatry; Director, Human Behavioral Pharmacology Laboratory, University of Chicago
Societies & Organizations in Illinois
- Chicago Psychedelic Healing and Spirituality Community — Community Meetup
- Chicago Psychedelic Community — Community Group
- Psychedelic Integration Group (Chicago) — Professional Integration Therapy
- Psychedelic Society of Chicago — Community
See how Illinois compares to neighboring states and find therapy options for residents: