Current Legal Status

Illegal — No Active Legislation

Psilocybin is a Schedule I controlled substance under South Carolina law. Possession is a misdemeanor for first offense; distribution is a felony.

Key Legislation

No psilocybin legislation has been introduced in the South Carolina General Assembly.

Clinical Trials

Medical University of South Carolina (MUSC) in Charleston has conducted MDMA and psilocybin research. Check ClinicalTrials.gov for Charleston-area enrolling studies.

Advocacy Organizations

No South Carolina-specific psychedelic advocacy organizations are currently active. MUSC researchers are active in national psychedelic research networks.

Related Resources

People in South Carolina

See how South Carolina compares to neighboring states and find therapy options for residents: