Important: These dose ranges are educational guidelines based on typical strain potency — they are not medical advice and not a prescription. Individual response to psilocybin varies significantly based on body weight, metabolism, prior experience, set and setting, and batch-to-batch potency variation. Always weigh doses on a milligram-accurate scale (0.01g resolution minimum; 0.001g for high-potency strains). Start at the lower end of any range you haven't experienced before. This calculator does not account for individual factors that a licensed facilitator or physician would assess. If you are accessing psilocybin through a licensed Oregon or Colorado service center, your facilitator will determine appropriate dosing.

Understanding Potency Differences

Psilocybin content varies dramatically between strains. A "2 gram dose" means something very different depending on what strain you're working with:

Strain Typical Psilocybin % Potency Tier vs. Golden Teacher
Golden Teacher~0.70%Standard
B+~0.75%Standard1.1×
Z-Strain~0.70%Standard
Cambodian~0.70%Standard
Ecuador~0.70%Standard
Amazonian~1.10%Moderate-high1.6×
McKennaii~1.10%Moderate-high1.6×
Penis Envy~1.90%High2.7×
Albino Penis Envy~2.10%Very high

Potency values are approximations from analytical testing aggregates. Actual potency varies between cultures, grow conditions, and individual harvests. These figures represent typical values, not guarantees.

Related Resources