National Harm Reduction Coalition — Psychedelics Program

The National Harm Reduction Coalition (NHRC) is the largest harm reduction advocacy and training organization in the United States, known primarily for work on opioid overdose prevention (naloxone distribution, syringe access) and drug checking. Their psychedelics program — a newer initiative — applies the NHRC's established harm reduction frameworks to psychedelic substances. The psychedelics program provides downloadable harm reduction guides for psilocybin use, training curricula for community organizations and healthcare providers on responding to difficult psychedelic experiences, and policy advocacy connecting psychedelic harm reduction to broader drug decriminalization frameworks. The NHRC's national network of harm reduction organizations provides a distribution channel that psychedelic-specific organizations lack. For communities and providers outside the psychedelic specialist ecosystem, NHRC's psychedelics harm reduction materials are often the most accessible entry point to evidence-based guidance.