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Psilocybin and Neuroplasticity: What BDNF and the Plastic Window Mean for Therapy
From Lex Fridman Podcast on YouTube
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34:00
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Science & Research
About This Video
A deep dive into psilocybin and neuroplasticity — BDNF upregulation, the plasticity window, and what the Yale dendritic spine study means for how we understand psilocybin's lasting effects.
Key Takeaways
- BDNF is upregulated within hours of psilocybin administration
- Dendritic spine density increases 10% in prefrontal cortex
- The neuroplasticity window lasts approximately 2-4 weeks
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