Andrew Gallimore, Ph.D.
Computational Neurobiologist; DMT Researcher; Author
Computational neurobiologist whose theoretical and pharmacological research on DMT — including proposals for sustained intravenous DMT infusion — represents some of the most rigorous scientific thinking about the mechanisms underlying intense psychedelic states.
Biography
Andrew Gallimore is a computational neurobiologist and pharmacologist who completed postdoctoral work at Cambridge and has since worked at the intersection of neuroscience, pharmacology, and consciousness science. His scientific focus is DMT (N,N-dimethyltryptamine) — the most potent naturally occurring psychedelic compound — and he has produced some of the most rigorous theoretical work in the field on what DMT does to the brain and why.
Gallimore's 2016 paper in Frontiers in Neuroscience, co-authored with Rick Strassman, proposed a protocol for using intravenous DMT infusion to sustain the typically brief DMT state for long enough to conduct systematic neuroimaging research. This pharmacokinetic protocol — which adjusts infusion rates to maintain target plasma concentrations — was subsequently implemented by Christopher Timmermann and colleagues at Imperial College London, producing the first sustained DMT neuroimaging studies. Gallimore's theoretical work made the Imperial College DMT research possible.
Beyond the infusion protocol, Gallimore has developed theoretical frameworks for understanding why DMT produces the structured, consistent, and often elaborate experiences that users report — including apparent contact with non-human entities, complex geometric architecture, and experiences of alternative realities. His book 'Alien Information Theory' (2019) develops a rigorous theoretical framework for understanding these phenomena, drawing on neuroscience, information theory, and physics without resorting to supernatural explanation.
His earlier book 'Reality Switch Technologies' (2022) provides a more accessible account of how different psychedelic compounds alter consciousness through distinct pharmacological mechanisms — a comparative pharmacology of the psychedelic state.
Organizations
Why They Matter to the LearnShrooms Community
Gallimore's work on sustained DMT infusion protocols enabled the landmark Imperial College London DMT studies that represent the current frontier of psychedelic neuroimaging. His theoretical frameworks for understanding the structured content of intense psychedelic states provide conceptual tools that the field needs as it moves beyond outcome measurement toward mechanistic understanding of what these compounds actually do to consciousness.
