Can you test psilocybin potency at home? What methods exist?
48 replies · Safety & Harm Reduction
Is there any way to test the potency of mushrooms at home? I grow my own and different flushes seem to vary significantly. I know commercial testing exists but I want something simpler for rough calibration.
Ehrlich reagent test is the primary home reagent for psilocybin. It turns purple/violet in the presence of indole alkaloids (psilocybin, psilocin). It does NOT quantify potency and does NOT distinguish psilocybin from other indoles. What it tells you: whether indole alkaloids are present at all — good for confirming you have something active rather than an inert mushroom or a different drug. Not a potency test.
For rough potency calibration between flushes: the blue color from bruising is caused by psilocin oxidizing. More intense bluing generally (but not precisely) correlates with higher psilocin content. This is a very rough proxy — don't use it to make dosing decisions with confidence. It can tell you 'this flush seems more potent than usual' at the rough level. For actual quantification, you need HPLC or mass spectrometry — available commercially through services like Psilera, Psilli, or academic labs.
Practical calibration approach that doesn't require any testing: standardize your dosing by weight and keep detailed notes on how each dose affects you. If a 2g dose of one flush feels significantly different from another flush, you've identified a potency difference. Reduce dose conservatively on unknown/new batches. The most reliable dose-response data you'll ever have is your own consistent documentation.
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