Colorado passed Proposition 122 in November 2022, following Oregon's model. It's been two years since the vote and I'm trying to understand what's actually operational in Colorado now, as of 2026. The information I find seems to be outdated.
Reply #1 · ▲ 89 upvotes
Updated as of early 2026: Colorado's Natural Medicine Health Act (Proposition 122) established a similar licensed healing center model to Oregon. The Colorado Department of Regulatory Agencies (DORA) and the State Licensing Authority (SLA) are the regulatory bodies. Unlike Oregon, Colorado Prop 122 includes psilocybin mushrooms plus mescaline, ibogaine, and DMT under the program — a broader scope than Measure 109. Healing centers began licensing in late 2024, and some operational healing centers were offering services in 2025.
Reply #2 · ▲ 71 upvotes
The key difference from Oregon: Colorado's Prop 122 included a personal use component. People 21+ may possess, grow, and share (not sell) natural psychedelic substances without the licensed center framework. This is effectively personal decriminalization alongside the licensed access system. Oregon didn't include this — Oregon only licensed commercial access.
Reply #3 · ▲ 54 upvotes
Practical state for visitors: healing centers are concentrated in Denver/Boulder metro area and in some mountain communities. Costs are broadly similar to Oregon. If you're planning to visit Colorado for a session, check the DORA licensing database for currently licensed healing centers and facilitators — the landscape is still developing and new centers are being licensed regularly.
64 more replies — forum posting coming soon.
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